Guided imaging
The phone records consistent facial images for comparison over time.
Science
Delivery is a physical problem.
A formulation begins with ingredients. Delivery depends on what happens when that formulation meets the skin: the barrier, the payload, the interface, and the conditions of the session.
The Skin Barrier
Skin is designed to keep things out.
The stratum corneum is the principal barrier to topical transport. Molecular size, charge, formulation, and surface conditions all influence the delivery event.
Surface concentration alone does not establish where a payload travels or how much reaches a particular layer. Application and deposition are different questions.
The formula is only half the system.
Stratum corneum
Viable epidermis
Dermis
The First Payload
PDRN brings the delivery question into focus.
PDRN consists of DNA-derived polymer fragments. Their size, hydrophilicity, and charge make the conditions of application especially important.
PDRN-01 pairs a defined payload with a defined AXIS session so the formulation and instrument operate as one system.
Payload characteristics
polymeric DNA fragments
broad molecular-weight distribution
hydrophilic character
polyanionic charge
Precision Skin Intelligence
Two views of the skin. One connected record.
The phone records visible facial appearance through guided imaging. AXIS measures local interface conditions before and during each session. Imaging follows visible change. Interface sensing supports controlled operation. Completed sessions connect both views through a personal history built over time.
Interface sensing
AXIS monitors local contact, electrical, and thermal conditions around the treatment surface.
Protocol control
Live interface signals help maintain operation within the protocol's defined limits.
Personal history
Completed sessions and periodic imaging create a connected record of use and visible change over time.
Visual imaging and interface measurements remain distinct signals. Together, they create a more complete record without asking either measurement to stand in for the other.
The Delivery Interface
One surface. Coordinated operation.
The treatment head coordinates payload application, controlled operation, guidance, and sensing in a single interface.
Defined contact
Establishes repeatable placement for a controlled session.
Payload application
Applies the compatible formulation in sequence.
Controlled operation
Runs the selected protocol while monitoring interface conditions.
Guided use
Coordinates preparation, timing, pauses, and completion.
Validation
From instrument operation to skin response.
A session record shows how AXIS operated. Direct physical testing establishes payload deposition. Controlled human evaluation establishes tolerability and cosmetic outcomes. Each layer answers a different question.
Operation
Did AXIS run as intended? Contact, electrical and thermal conditions, programmed phases, and session completion.
Deposition
Where did the payload go? Recovered quantity measured across sampled skin layers through direct physical testing.
Response
What followed? Tolerability and cosmetic outcomes evaluated under a defined protocol.
Selected scientific literatureView literature by subject
These studies inform the scientific basis and design of AXIS. They do not establish AXIS-specific performance.